Fresh from her recent defeat at the Battle of Canis Major, the Dark Queen decides to take out her aggressions on her archenemies, the Battletoads. The 'Toads and their mentor, Professor T-Bird, are currently escorting Princess Angelica home to her father, the Terran Emperor. During a rest stop, Pimple takes Angelica out for a drive in the Toadster, but the vehicle and its occupants are swallowed up by the Dark Queen's ship, the Gargantua, and taken to her tower on planet Ragnarok. Rash and Zitz are quickly sent down to Ragnarok's surface to rescue their friends, unaware of the dangers that await them, but willing to chance it all on their rescue mission.