In the 22nd century, mankind has begun to emigrate into outer space. Three huge space colonies were constructed at a Lagrange point: the Isis Cluster; two artificial biospheres, named Land-1 and Land-2, and a satellite. In the year 0024 (55 years after the cluster was constructed), a biohazard outbreak occurred on Land 2. All attempts at contact were met with nothing but static. Now a research team led by their pilot, Gene, approaches Land-1. Upon arrival, the team was attacked by a group of robots and the shuttle exploded due to the damage during the battle, knocking Gene out immediately after. Gene then awakened in the medical centre of Isis City to find one of his team members fatally wounded. Said team member informs Gene that their goal was to find Stolte, a researcher at Land-2's Bio Research Lab, and Gene sets off to find him, wherever he is in Land-2.