The player character has just inherited a hotel, The Last Resort, belonging to their deceased uncle, Thurston Last. The hotel is inhabited by nine muses. As the player character enters the hotel, it becomes clear that it is no longer a hospitable place. Its wacky inhabitants live in fear of a pair of squatters known as the Toxic Twins. Only the aeroplane-man Salty is brave enough to wander around and talk to the player character. The player's goal is to reconstruct "The Muse Machine" and banish the Toxic Twins.