While patrolling the city one day, Spider-Man spots several thugs attempting to rob a bank and stops them. Later that night, after having dinner with his friends Mary Jane Watson (for whom he has hidden feelings) and Harry Osborn (who despises Spider-Man, blaming him for his father's death), Peter spots a van being chased by the police and follows it to the Queensboro Bridge, where the chase has led to a massive traffic accident. As Spider-Man, he rescues several endangered civilians and cops before following the van to a warehouse, where he finds thugs unloading explosives. While fighting the thugs, the explosives provoke a massive fire, but Spider-Man is able to put out the flames and deal with the remaining crooks. Later, Harry introduces Peter to Dr. Otto Octavius, a nuclear scientist who is trying to make a fusion power experiment, sponsored by Oscorp, which would provide an unlimited power source to Manhattan. Octavius quickly befriends and begins to mentor Peter. While handling hazardous materials, Octavius wears a harness of powerful robotic tentacle arms with artificial intelligence. During a public demonstration Peter and Harry attend, a power spike causes the fusion reactor to destabilize. Octavius refuses to shut down the reactor, which goes critical—killing his wife and burning the inhibitor chip blocking the arms from his nervous system. Peter, as Spider-Man, shuts the experiment down, destroying it in the process. Later, the arms' AI begins to influence Octavius, and he becomes the villain Doctor Octopus, seeking to complete his work at all costs.