Kyuumei-hen is a direct sequel to the first Twilight Syndrome game, continuing the spooky adventures of the three brave and reckless high-school girls: Yukari, Mika, and Chisato. The first mystery involves a girl named Sakura Himegami, who was killed in an accident many years ago; apparently, her ghost is still around somewhere. The trail leads to an abandoned path in the mountains; Mika decides to venture there, while the other two are going back to school at night, hoping to find more clues.