Genius Yamada, a mad scientist with a plan for world domination, has taken over a game machine at the You&Me Kamiyoga game center in Kamiyoga, Setagaya-ku, Tokyo, for starters. Yuki Ito, a clerk at the game center, tries to solve the problem during her working hours by forcibly piecing together her own collection of game boards and asking the protagonists of each game to help her defeat Genius Yamada.