The player assumes the role of the titular Jantoushi Doraou, a master mahjong Saint who resides in Sanctuary and is committed to protecting the goddess Atenaide. Unfortunately, the villainous Mahjong warlock Jankou invades Sanctuary and seemingly kidnaps Atenaide! It's Doraou's duty to rescue her from the clutches of this fiend, and he sets off on a journey to gather the other Mahjong Saints and journey to Jankou's castle to rescue her. This journey winds through a number of towers with guardians based on the Chinese Zodiac; this is a direct parody of Saint Seiya, where the Gold Saints are based off of the Greco-Roman zodiac.