Mahou Sensei Negima!? Neo-Pactio Fight!! is a 3-D fighting game. The arenas in the game are in full-time 3D, and the characters can move in any direction, as well as jump. Up to four players can play in Battle Mode. Controls are operated by using both the Wii Remote and Nunchuk (the Classic Controller and Wii Remote (used sideways) are also supported as control methods). Certain attacks and moves involving quickly moving the Wii Remote left and right or up and down. By getting a Pactio Card, one can activate a Pactio transformation like in Negima!?, randomly (though possible to control) becoming one of the three different forms: Armor (powerful version of your character, using a very powerful attack), Cosplay (character dresses up in costumes, and boosts the characters abilities), and Suka (or "Miss", in which your character is transformed into a weak super-deformed animal, such as a Kappa in Kaede's case).